Studying on creation of hybridomas producing monoclonal antibody specific for progesteron
نویسندگان
چکیده
منابع مشابه
Early history of specific antibody-producing lymphocyte hybridomas.
Specific antibody-producing lymphocyte hybridomas have become a major tool of research in tumor immunology. The production of monoclonal antibodies by lymphocyte hybrido mas in vitro or in ascites fluid in vivo dates from the experiments of Kohler and Milstein (2), followed closely by many others. The purpose of this correspondence is to direct attention to tetraploid murine lymphoma cell lines...
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Human-human hybridoma technology was used to immortalize human B lymphocytes from patients with acute myeloid leukemia (AML) to study the antigenic repertoire of the humoral immune response against the patients' own leukemia cells and against leukemic cells from other patients. Nine fusions were done with lymphocytes from seven AML patients, and all with the human RH-L4 B lymphoma line as malig...
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Two cases of Waldenström's macroglobulinaemia have been seen at University College Hospital, Ibadan in the last four years, Case 1 was a 30-year-old soldier who presented with splenomegaly and anaemia, was treated with chlorambucil, and had a complete remission sustained for over two years. Case 2 was a 58-year-old retired civil servant who presented with very severe anaemia and also splenomega...
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mammalians express several subclasses of the igg molecule. in human being there are four homologous igg subclasses, each of which is structurally unique and has different functions. quantification of igg subclasses is fundamental to clinical assessment and diagnosis of many diseases as such assessments depends on the availability of subclassspecific antibodies (abs), particularly monoclonal ant...
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ژورنال
عنوان ژورنال: TAP CHI SINH HOC
سال: 2012
ISSN: 0866-7160,0866-7160
DOI: 10.15625/0866-7160/v32n3.713